Faecal carriage of extended-spectrum beta-lactamase-producing Enterobacteriaceae in healthy volunteers and hospitalized patients in Ouagadougou, Burkina Faso: prevalence, resistance profile, and associated risk factors
نویسندگان
چکیده
Background: Extended spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-PE) are a serious challenge to patients’ treatment. The aim of this study is determine the prevalence ESBL-PE, investigate associated resistance, and analyze risk factors for acquisition ESBL-PE.Methodology: A cross-sectional was conducted on healthy volunteers inpatients. After obtaining informed consent, rectal swabs were collected from each participant isolation Hektoen enteric agar containing 4µg/L cefotaxime. isolates identified using biochemical tests ESBL production confirmed by double-disc synergy test amoxicillin clavulanic acid. Antibiotic susceptibility isolate done disc diffusion method interpreted recommendations European Committee Antimicrobial Susceptibility Testing (EUCAST) clinical breakpoints version 5.0.Results: During period, faecal ESBL-PE among participants 54.5% (103/189); 53.5% 55.7% inpatients (p=0.87). major Escherichia coli (71%) followed Klebsiella pneumoniae (16%). in hospitalized patients resistant norfloxacin (84.2%), cotrimoxazole (89.5%), gentamicin (7.0%). (86.2%), (82.8%), (1.7%).Gender, age, previous antibiotic use not significantly with carriage (p=0.51).Conclusion: high worrying. There an urgent need develop measures monitor limit spread these multidrug-resistant organisms healthcare facilities community Burkina Faso.
 Keywords: carriage, volunteers, inpatients, Faso
منابع مشابه
High prevalence of extended-spectrum ß-lactamase producing enterobacteriaceae among clinical isolates in Burkina Faso
BACKGROUND Nothing is known about the epidemiology and resistance mechanisms of extended-spectrum ß-lactamase-producing Enterobacteriaceae (ESBL-PE) in Burkina Faso. The objective of this study was to determine ESBL-PE prevalence and to characterize ESBL genes in Burkina Faso. METHODS During 2 months (June-July 2014), 1602 clinical samples were sent for bacteriologic investigations to the mic...
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متن کاملRisk factors for the acquisition of extended-spectrum beta-lactamase-producing Enterobacteriaceae in hospitalized children.
1 Departamento de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay 2 Departamento de Pediatría, Centro Hospitalario Pereira Rossell, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay 3 Departamento de Farmacología y Terapéutica. Hospital de Clínicas “Dr. Manuel Quintela”, Facultad de Medicina, Universida...
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OBJECTIVES To determine the occurrence of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in Bahrain. METHODS Retrospective analysis of records (January 2005-December 2006) at the Microbiology Laboratory of the Salmaniya Medical Complex, Bahrain which is the major national diagnostic laboratory. RESULTS Out of a total of 11,886 member of family of Enterobacteriaceae iso...
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ژورنال
عنوان ژورنال: African Journal of Clinical and Experimental Microbiology
سال: 2021
ISSN: ['1595-689X']
DOI: https://doi.org/10.4314/ajcem.v22i2.7